First-order Compartment Model
This model arises from
pharmakinetics, which is the dynamics of drug absorbtion,
distribution and elimination. The factors in the model are
rate of absorbtion and rate of elimination, which give rise to
a stiff ODE system that decays exponentially. Since there are
biological considerations, a nonlinear fit method is often
more useful than the ODE solution. In the function,
d0 is the initial does, Ke is the
elimination rate constant, Ka is the absorbtion
rate constant, and Cl is the measure of the
body's ability to eliminate the drug or
clearance.
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